Clicking the “Publish” button within the “Publish Web” dialog will publish a web application (and optionally associated database schema/content) to a remote web server. 

VS 2010 also supports a “one click” publish toolbar that you can add to your IDE to quickly publish/re-publish your project without having to load the  “Publish Web” dialog:

Just select your publish profile from the toolbar drop-down and then click the publish icon to the right of it to begin deploying your application.